Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Kida, Y.; Higashimoto, Y.; Inoue, H.; Shimizu, T.; Kuwano, K.
    A novel secreted protease from Pseudomonas aeruginosa activates NF-kappaB through protease-activated receptors (2008), Cell. Microbiol., 10, 1491-1504.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.24.26 extracellular
-
 Pseudomonas aeruginosa
-
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.24.26 100000
-
 x * 100000, SDS-PAGE Pseudomonas aeruginosa

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.26 Pseudomonas aeruginosa
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.26 additional information large exopeptidase LepA activates nuclear factor kappa-kB-driven promoter through human protease activated receptors PAR-1, -2 or -4 and cleaves the peptides corresponding to the tethered ligand region of human PAR-1, -2 and -4 at a specific site with exposure of their tethered ligands Pseudomonas aeruginosa ?
-
 ?
3.4.24.26 PAR-1 peptide + H2O cleavage at the R41-S42 site Pseudomonas aeruginosa ?
-
 ?
3.4.24.26 PAR-2 peptide + H2O cleavage at the R36-S37 site Pseudomonas aeruginosa ?
-
 ?
3.4.24.26 PAR-4 peptide + H2O cleavage at the R47-G48 site Pseudomonas aeruginosa ?
-
 ?

Subunits

EC Number Subunits Comment Organism
3.4.24.26 ? x * 100000, SDS-PAGE Pseudomonas aeruginosa

Synonyms

EC Number Synonyms Comment Organism
3.4.24.26 LepA
-
 Pseudomonas aeruginosa